Friday, 6th May
8th Modern Solid Phase Peptide Synthesis & Its Applications Symposium 2022
Days
Friday, 6th May
Saturday, 7th May
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Speakers
Registration Open
8:00AM - 10:30AM
Friday, 6th May
Welcome and Opening
10:30AM - 10:45AM
Friday, 6th May
Session 1 Peptide synthesis and modification
10:45AM - 12:45PM
Friday, 6th May
Chairs: Craig Hutton & K. Johan Rosengren
Sponsored by:
Electrifying Peptide Synthesis
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Lara R Malins
A plug and play approach for the synthesis of grafted cyclotides
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Johannes Koehbach
Metal-peptides complexes as disulfide surrogates for bioactivity
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Adam C Kennedy
Synthesis of CLipPA analogues of the antimicrobial peptide, paenipeptin C΄
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Juliana T. W. Tong
Application of alkylthioaryl linkage in macrocyclic peptidomimetic design
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Wenxiao K Yue
To be provided
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Ethan Goddard-Borger
Lunch
12:45PM - 2:00PM
Friday, 6th May
Session 2 Peptide drugs
2:00PM - 3:45PM
Friday, 6th May
Chairs: Max Cryle & Susan Northfield
Sponsored by:
GnRH Peptide/Adjuvant Conjugate Vaccine Candidates for Veterinary Immunocastration
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Istvan Toth
A novel antagonist of RXFP4-r reveals a target for the treatment of colon motility disorders
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Ruslan Pustovit
Advancement in the synthesis of human and mouse C5a, and the development of a hC5a lanthanide-labelled probe
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Declan M Gorman
Cyclic Lipopeptide Delivery Systems for Group A
Streptococcus
Peptide Antigens
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Rachel J Stephenson
Special Delivery: A New Class of Peptide Antibiotics that Acts by Enhancing the Host Innate Immune Response
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Raymond S Norton
Tea Break
3:45PM - 4:15PM
Friday, 6th May
Sponsored by:
Session 3 Peptide chemistry
4:15PM - 6:00PM
Friday, 6th May
Chair: Lei Liu
Sponsored by:
New Methods for Construction of Complex Peptide Macrocycles
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Gong Chen
Divergent construction of ꞵ-thiolated/selenolated amino acids by asymmetric decarboxylated Giese reaction
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Ping Wang
Novel Vinyl Esters for Peptide Synthesis
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Junfeng Prof. Zhao
Hypervalent Iodine Reagents for Peptide and Protein Modification
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Jérôme Waser
Break
6:00PM - 6:30PM
Friday, 6th May
Poster Session with drinks
6:30PM - 7:30PM
Friday, 6th May
Sponsored by:
Development of peptide therapeutics for neurodegenerative diseases
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Azin Amin
Macrocyclic Peptides from Unmodified Linear Precursors: A Reductive Amination Approach
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Hayden Bell
Cyclisation of Linear Peptides from Unmodified Starting Residues Using Reductive Amination Chemistry
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Hayden Bell
Late-stage modification of peptides and proteins at cysteine with diaryliodonium salts
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Stephen A Byrne
Rational design and evaluation of multi-functional white adipose tissue-targeting peptides anti-obesity effects
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Lai Yue Chan
Chemical glycosylation of glucose homeostasis-regulating peptides including insulin and glucagon.
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Chaitra Chandrashekar
Modular Synthesis of Trifunctional Peptide-oligonucleotide Conjugates via Native Chemical Ligation
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Mohadeseh Dastpeyman
Semisynthesis of mycobacterial lipoproteins
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Joshua J Dilly
Development of peptide based subunit vaccine for prevention of Tuberculosis
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Viet Tram Duong
Synthesis of covalent peptide inhibitors for the Chikungunya virus non-structural protein-2 protease
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Junming He
Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity
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Candace YT Ho
Towards the synthesis of the unique pseudo-homodimer aD-VxXXB
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Thao Ho
An inherently fluorescent peptide constraint influences secondary structure and enables imaging of cell permeable peptidomimetics
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Aimee J Horsfall
Polyethyleneimine quantity and molecular weight influence its adjuvanting properties in liposomal peptide vaccines
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Wenbin Huang
Rapid one-pot iterative diselenide-selenoester ligations using a novel coumarin-based photolabile protecting group.
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Lucas Kambanis
Electrochemically enabled late-stage modifications of peptides
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Dhanya Karipal Padinjare Veedu
Comparison of rod and worm shaped polymer-based nanoparticles for peptide delivery to treat Group A Streptococci infection
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Prashamsa Koirala
Photooxidation of oxazoles – a new approach to solid-phase peptide synthesis
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Chloe N Larcombe
Using chirality to induce permeability in somatostatin analogues
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Travis Lay
Fmoc group removal with NaOH in mixtures of water and green solvents during SPPS on biodegradable resin-ℇ-poly -Lys resin
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Feng Lin
Design, Synthesis and Analysis of BDNF mimetic peptides
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Qingqing Lin
An Electrochemical Approach to Designer Peptide α‐Amides Inspired by α‐Amidating Monooxygenase Enzymes
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Yutong Lin
Total Chemical Synthesis of a Biologically Active Insulin Dimer
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Mengjie (Oscar) Liu
Poly (hydrophobic amino acid) as a delivery system for protein subunit vaccines
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Lantian Lu
Development of glycotopes to protect against streptococcus pyogenes using solid-phase synthesis
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Asmaa Mahmoud
Chemo-enzymatic total synthesis of Vancomycin Analogues
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Edward Marschall
Design and synthesis of cell-permeable anti-microbial peptides that act by inhibiting the SPSB-iNOS interaction
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Macgregor A Matthews
Synthetic strategies towards the total synthesis of sactipeptide natural products.
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Karen Milewska
Peptide stapling using α-bromoketone-based linkers
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Richard Morewood
Expanding the versatility and scope of the oxime ligation
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Markus Muttenthaler
Development of mannosylated peptide-based vaccine against group A
streptococcus
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Ummey Jannatun Nahar
Discovery of cyclic peptide ligands to the SARS-CoV-2 spike protein using mRNA display
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Alexander R Norman
Peptide drug conjugates as novel antimalarials
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Isabella Palombi
The Total Chemical Synthesis and Biological Evaluation of the Cationic Antimicrobial Peptide, Brevicidine
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Dennise M Palpal-latoc
Synthetic pathways for covalently tethered cyclic peptides
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William Parsons
Continuous Chromatography of Peptides
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Keith Porter
Photoaffinity labelling for the elucidation of mycocyclosin target protein(s)
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Hannah Ryan
Probing the Chemical Space Surrounding Antimicrobial Peptide Capitellacin via Variable Cyclic Analogues Synthesized by means of Flow-SPPS
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Oscar A Shepperson
Modifying retro-inverso peptides with N-terminal warheads
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Laura Shuttleworth
Development of Peptide-based Vaccines against Hookworm
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Mariusz Skwarczynski
Synthesis of interchain dicarba insulin analogues
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Amy L Thomson
Evaluation of efficient non-reducing enzymatic and chemical ligation strategies for complex disulfide-rich peptides
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Hue Tran
Biocompatible peptide bicyclisation using dicyanopyridine amino acids
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Sven Ullrich
Peptide-bismuth bicycles
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Saan Voss
Poly(hydrophobic amino acids) vaccine delivery system for intranasal immunization against Group A streptococcus (GAS)
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Jingwen Wang
Engineering of novel insulin-like peptide analogues for the treatment of colon motility disorders
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Hongkang Wu
Blood-brain barrier permeable antisense oligonucleotides for Spinal Muscular Atrophy
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Yuan Qi Yeoh
In vitro
chemoenzymatic approach reveals the recognition and cyclisation mechanism of biarylitide P450
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Yongwei Zhao
Investigating the Biosynthesis of Dha/Dhb in Lexapeptide.
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Emily S. Grant-Mackie
A Concise Synthetic Strategy Towards the Novel Calcium-dependent Lipopeptide Antibiotic, Malacidin A and Analogues
1
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Louise A Stubbing
Welcome Reception
7:30PM - 9:30PM
Friday, 6th May
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